Ferritin as a drug/vaccine carrier
Ferritin, a blood cell protein that contains iron, has a unique structure and biochemical properties that can disassembly/reassembly at certain conditions.
As a result, therapeutic agents can be loaded into the inner cavity of these blood cell proteins.
In this project, we combined experiment and simulation results to test the stability, purity and other aspects of ferritin-complexes, as well as their docked-structure with epitopes in different conditions, with the aim to provide more information and understanding on how ferritin performs under these conditions. Hopefully in the future, ferritin will be widely used not only to fight against infectious diseases but also in cancer treatment and other disorders.
Chemical Engineering and Advanced Materials
An Xuan Hoang Nguyen
Martin Leang Yiv