Using hypercubes in sepsis
Sepsis is a life-threatening organ dysfunction caused by the body’s overwhelming response to infection.
It can lead to organ failure and death, thus early detection and management is crucial.
The aim of my project is to investigate the use of gene expression data to produce a quick and reliable test for sepsis. Gene expression data consists of a large number of genes and small number of observations. Investigating all possible combinations of genes that are associated with sepsis would be similar to finding a needle in a haystack - meaning it would take a lot of time!
This project uses a recently introduced method by Cox & Battey motivated by a hypercube geometry. This method allows to select sets of combinations of genes and dramatically reduces the time needed.
Aline Teresa Kunnel